CLR BERLIN

The CLR Range

Activ-Ingredient is the exclusive distributor for CLR Berlin in Australia and New Zealand markets.

CLR develops smart cosmetic active ingredients that work – for effective cosmetics. Make success simple with high-quality actives from CLR – for fine cosmetics since 1926.

The CLR Range

Activ-Ingredient is the exclusive distributor for CLR Berlin in Australia and New Zealand markets.

CLR develops smart cosmetic active ingredients that work – for effective cosmetics. Make success simple with high-quality actives from CLR – for fine cosmetics since 1926.

Wheat Germ Oil CLR

Wheat Germ Oil CLR is particularly suitable for skin protection concepts and the care of sensitive and severely dry skin and lips. Wheat Germ Oil has an extensive history of use. For centuries, it has been used for a wide variety of skincare applications, for instance for its healing properties and for the treatment of many different skin ailments.

Wheat Germ Oil CLR is obtained from freshly milled wheat germs renowned for their high antioxidant content.

St.John’s Wort Oil CLR

St. John’s Wort Oil CLR is particularly suitable for the care of dry, sensitive and problem skin, chapped lips, and in the support of irritated skin. St. John’s Wort has been traditionally used in medicinal applications to treat insect bites, sunburn, bruises and edema.

St. John’s Wort Oil CLR contains the lipophilic components of the aerial parts of the St. John‘s Wort plant (Hypericum perforatum), collected when in blossom and gently extracted in olive oil.

Carrot Oil CLR

Carrot Oil CLR is especially suitable for anti-aging skin care, sun and after-sun care, and all skincare concepts for obtaining an even and harmonious skin color. Carrots are renowned for their high content of ß-carotene, which is further enriched in Carrot Oil CLR to obtain optimal results for the skin, providing skin with much needed protection.
Carrot Oil CLR is a lipophilic extract of Daucus carota sativa in stabilized soybean oil, enriched with anti-oxidative ß-carotene to 3,300 IU/g.

Arnica Oil CLR

Arnica Oil CLR is suitable for a wide variety of skin and haircare concepts, such as anti–hair loss, relief for troubled skin, and after-sun care. Arnica is renowned for its ability to stimulate and heal the skin, which is illustrated by its extensive use in the treatment of bruises and sprains. It is also known for its calming and soothing properties.
Arnica Oil CLR is obtained by an extremely mild extraction of the blossoms of Arnica montana in stabilized soybean oil.

Calendula Oil CLR

Calendula Oil CLR is particularly suitable for skin and haircare concepts where soothing and calming properties are valued, such as baby care, care for sensitive skin, elderly skin and irritated scalp. Calendula has been extensively used in both traditional and modern medicine for its well-described
anti-inflammatory properties.
Calendula Oil CLR is obtained by an extremely mild extraction of the blossoms of Calendula officinalis in stabilized soybean oil.

Soluvit Richter NP

Soluvit Richter NP is suitable for a wide variety of skin and haircare concepts, such as the treatment of eye bags, dark circles, bruises and the care of tired legs and nails, but also for anti–hair loss.
Soluvit Richter NP is based on an extract of horse chestnut enriched with vitamins A, E, F, H (biotin) and vitamins of the B group. Horse chestnut has a rich history of use in traditional and modern medicine, especially for its stimulating and energizing properties. The vitamins show an extensive range of potential benefits for both skin and hair.

SedaplantTM Richter

Sedaplant™ Richter is applicable in a wide variety of skin and haircare concepts, such as baby care, and care for sensitive skin and scalp.
Sedaplant™ Richter contains potent mixtures of extracts from fennel, hops, chamomile, balm mint, mistletoe and yarrow, as well as urea and allantoin. All ingredients are well known and well appreciated in both traditional medicine and modern science, especially for their skin-healing and soothing properties.

HexaplantTM Richter

Hexaplant™ Richter is applicable in a wide variety of skin and haircare concepts, such as baby care, and care for sensitive skin and scalp.
Hexaplant™ Richter contains potent mixtures of extracts from fennel, hops, chamomile, balm mint, mistletoe and yarrow. All ingredients are well known and well appreciated in both traditional medicine and modern science, especially for their skin-healing and soothing properties.

Maricol S

Due to its film-forming and skin-protective properties, Maricol S is especially suitable for the care of dry and mature skin as well as skin stressed by negative environmental influences.
Maricol S is a native soluble collagen of marine origin, obtained from fish skin.

Ceramide Complex CLR TM PE-F

Ceramide Complex CLR™ PE-F supplies skin with structural elements and supports the recovery and maintenance of the skin’s healthy barrier function and water-holding capacity.

Ceramide Complex CLR™ PE-F contains phyto lipids in lamellar, liquid crystalline form. The plant-derived lipid mixture consists of phospholipids and sphingolipids. It is easily able to penetrate skin and also moisturizes hair.

GlycodermTM (P)

Glycoderm™ (P) is a liposomal moisturizer, where plant derived liposomal bilayers contain biotechnologically produced hyaluronic acid and natural blossom honey. Its liposomal structure supports quick absorption of hyaluronic acid and blossom honey.

Consequently, Glycoderm™ (P) constitutes a polyvalent approach toward skin hydration by supporting the maintenance and recovery of the skin’s lipid barrier function and supplying the skin with essential ingredients that are able to bind water and moisturize skin.

HygroplexTM HHG

Hygroplex™ HHG is a physiological moisturizer, specifically designed to be fully adapted to the water-binding capacity of human skin, containing ingredients similar to the Natural Moisturizing Factors (NMF) in the skin. It is extremely suitable for skincare concepts for dry and aged skin and can be used in any skincare application for any type of skin which needs hydration. It effectively moisturizes and smoothes the skin.

Additionally, it has shown to be a potent moisturizer for hair, increasing its water content and improving its mechanical properties.

Also available as Hygroplex™ WHN without hexyl nicotinate.

ProBarrierTM CLR

ProBarrier™ CLR, a suspension of waxy particles based on caprylic/capric triglycerides and Copernicia cerifera (carnauba) wax, is a highly technological skincare ingredient which creates a persistent but non-occlusive film on the skin.

It is especially designed for cosmetic formulations which aim to shield the skin against harsh environmental conditions, providing an extra layer of protection and an excellent light skin feel.

DayMoist CLRTM

DayMoist CLR™ potently and immediately increases the concentration of the natural moisturizing factors (NMF) in the upper layers of the skin, resulting in immediate and long-lasting moisturizing effects. These results were obtained by making use of Confocal Raman Microspectroscopy and analyzing skin capacitance.

DayMoist CLR™ also is a hair conditioner, improving hair combability and manageability. Additionally, it was shown to positively influence the mechanical properties of hair and to protect against fading of hair color in dyed hair. DayMoist CLR™ also effectively protects hair against heat that is applied during hair straightening.

DayMoist CLR™ is a complex of natural plant-derived active ingredients.

Vitamin F Forte

Vitamin F forte nurtures, protects and acts as a skin conditioner. It is particularly suitable for the treatment of dry, stressed and sensitive skin, potently supporting the skin in rebuilding and maintaining its natural healthy structure and functionality.

Vitamin F forte also is a strong hair conditioner, improving hair combability, and has shown to protect against hair breakage.

Vitamin F forte contains natural polyunsaturated essential free fatty acids originating from safflower oil, with a particularly high content of linoleic acid.

Also available as Vitamin F water-soluble CLR in watersoluble form. 

ModukineTM

Modukine™ is a milk-derived active ingredient which is specifically designed for the effective regenerative care of sensitive, dry and troubled skin. It is intended for any type of skin which shows chronic and pronounced inflammation.

Modukine™ acts as an extremely potent biological cell response modifier. It strongly reduces inflammatory processes in the skin at a cellular level and helps to restore skin barrier and normal skin functionality.

ProBioBalance CLRTM NP

ProBioBalance CLR™ NP activates cellular processes involved in cellular nutrition and helps activate detoxification processes. The metabolic activity of skin cells is increased, and the skin’s immune system strengthened and protected against environmental stress. The application of ProBioBalance CLR™ NP leads to reduction of skin inflammation and also actively prepares skin for external stresses.

ProBioBalance CLR™ NP consists of postbiotic bifido cultures which are suspended and disintegrated in a biologically active milk-based matrix.

PhytoDefense CLRTM

PhytoDefense CLR™ is especially designed for the care of hyper-reactive and irritable skin. It essentially reduces the sensitivity of skin by its goal-oriented approach to the most important features of sensitive skin: burning/stinging/itching sensations and skin redness. Skin irritations as well as skin redness are noticeably reduced.
PhytoDefense CLR™ is obtained from Magnolia grandiflora, known in traditional medicine for its potent calming and soothing properties.

Repair Complex CLRTM PF

Repair Complex CLR™ PF is a biotechnological anti-aging active, obtained from a lysate of probiotic bifidobacteria, which potently protects against UV-induced damage in the skin. UV radiation leads to skin cell damage and immunosuppression, a deactivation of the local immune system in the skin.
By effectively activating anti-immunosuppressive processes on the cellular level, Repair Complex CLR™ PF increases cellular repair and potently supports the skin’s endogenous protection mechanisms. Repair Complex CLR™ PF thus counteracts premature skin aging, i.e. photoaging.

LactokineTM Fluid PF

Lactokine™ Fluid PF is a multifunctional agent, suitable for a wide variety of skincare concepts. It effectively soothes and calms skin, accelerating the reduction of skin redness and irritation after external stresses. Additionally, Lactokine™ Fluid PF vitalizes and energizes skin cells and induces the synthesis of collagen, yielding skin smoothing and firming properties, thus making it a potent anti-aging product. In other in vivo studies Lactokine™ Fluid PF was shown to be very effective in skin lightening, reducing the production of melanin.
Lactokine™ Fluid PF contains a network of activated and stabilized signal molecules derived from milk.

FollicusanTM DP

Follicusan™ DP stimulates the functionality of the dermal papilla cells at the base of the hair follicles, thus counteracting premature hair loss. It increases the number of anagen hair follicles (growth stage) and decreases that of telogen hair follicles (resting stage). Hair density as well as cumulative hair thickness is increased.
Follicusan™ DP contains biologically active signaling proteins, ethyl panthenol (provitamin B5), inositol as well as acetyl cysteine and acetyl methionine in a water-ethanol medium.

PhytosanTM K

Phytosan™ K exerts a potent influence against skin aging. It activates cellular repair processes, supporting the maintenance of cellular integrity and energy after UV irradiation. Both are important factors in counteracting photoaging.
Phytosan™ K also has potent regenerative effects, such as stimulation of collagen synthesis. This results in improved skin firmness and smoothness and a reduction of wrinkle depth. Phytosan™ K counteracts biological and UV-induced premature aging of the skin.
Phytosan™ K contains proteins, glycoproteins, and polysaccharides isolated from organic soybeans (GMO-free).

SyriCalmTM CLR (PC)

SyriCalm™ is a natural product derived from Poria cocos and Phragmites. It effectively reduces inflammation and strongly supports skin in dealing with external stresses.
Additionally, SyriCalm™ is designed to give effective support where the skin is challenged by environmental stress, e.g. shaving, depilation or daily hygiene. It helps the skin recover its natural balance.
Available as SyriCalm™ CLR (PC) and SyriCalm™ CLR.

MPCTM -Milk Peptide Complex

MPC™ reduces the visible signs of aging by reactivating skin cells and inducing the production of extracellular matrix molecules in the dermis, such as collagen Type I, hyaluronic acid and fibronectin. In vivo studies have shown that formulations with MPC™ make the skin firmer and improve its elasticity. MPC™ quickly and effectively reduces wrinkle depth and improves the structure of the skin.
MPC™– Milk Peptide Complex contains a complex of activated natural signaling molecules derived from milk, such as TGF-β.

BelidesTM ORG

Belides™ ORG is a natural skin-lightening agent, derived from organic daisy flowers (Bellis perennis). It is suitable for any skincare concept providing even and luminous complexion and radiant skin.
Belides™ ORG’s action is based on a potent, multifaceted reduction in the activity of melanocytes. Belides™ ORG influences different cellular pathways involved in melanogenesis, encompassing the reduction of cellular signaling, tyrosinase transcription, tyrosinase activity and melanosome transfer. These actions lead to even pigmentation and make age spots less visible.
Also available as Belides™ NP.

ProRenew Complex CLRTM

ProRenew Complex CLR™ acts on essential features in the aging process of the skin, its ability to successfully adapt to a constantly changing environment and to effectively renew itself.

ProRenew Complex CLR™ positively influences the speed and quality of epidermal growth. It has shown to effectively promote desquamation, the shedding of dead cells. ProRenew Complex CLR™ is beneficial for both the health of skin and the skin microbiota. It balances and protects the skin microbiota and supports it in dealing with day-to-day stress.

ProRenew Complex CLR™ also improves the condition of the scalp and makes it less oily. It additionally leads to perceivable reduction of the sensitivity of the scalp, makes scalp tangibly healthier and reduces attributes related to dryness of the scalp. ProRenew Complex CLR™ provides important support for the skin and the scalp, even from rinse-off formulations.

JuvenEye CLRTM

Based on a synergistic combination of extracts of Hieracium pilosella and the flowers of Bellis perennis, JuvenEye CLR™ addresses the most important dermatological processes in the formation and persistence of dark circles. It activates vital processes which allow for the breakdown of heme, which is both dark-colored and plays an important role in the etiology of dark circles. JuvenEye CLR™ also activates dermal draining, through its ability to increase the production of VEGF-C. Excess fluids, electrolytes and immune cells are drained away more effectively. With JuvenEye CLR™ melanin deposition in the skin is reduced and overall skin health is improved.

In in vivo studies where JuvenEye CLR™ was compared with a corresponding placebo-formulation it could be seen that JuvenEye CLR™ clearly reduces the visibility of dark circles. Both the color and the surface area of dark circles were reduced significantly.

MultiMoist CLRTM

MultiMoist CLR™ activates production of the vitamin D receptor (VDR) and promotes the VDR’s activation. MultiMoist CLR™ also potentiates the effect of vitamin D. As a consequence the skin becomes more moisturized. By making use of 5 different objective instrumental approaches, the immediate and long term moisturizing properties of MultiMoist CLR™ were convincingly proven. Additionally, the activity of MultiMoist CLR™ was proven in a consumer study, where the subjective improvement of skin moisture content, skin smoothness and the look of skin were confirmed.

In addition, MultiMoist CLR™ binds water in the cortex of hair, improving a variety of important hair qualities. It is a hair conditioner, improving its combability and handling. MultiMoist CLR™ also protects against color fading caused by repeated washing with shampoo. It dramatically reduces hair breakage from combing and MultiMoist CLR™ has a strong impact on static flyaway too. Hair frizziness is significantly reduced as well.

MultiMoist CLR™ consists of a powerful synergistic blend of fructooligosaccharides and beta vulgaris (beet) root extract.

G+C Complex CLRTM

G+C Complex CLR™ is based on almost 50 years of scientific research on the effect of Bifida Ferment Lysate on skin aging. With its natural next generation approach, it acts on the core of skin aging, the ability to compensate for the threefold negative effects of sunlight on the biogenetic code of skin: DNA damage, immunosuppression and dysregulation of the circadian rhythm. G+C Complex CLR™  provides essential support to the skin cells. It acts on UV-induced immunosuppression and brings balance to the circadian rhythm of skin cells, allowing for effective DNA repair.

G+C Complex CLR™ induces the repair of persistent CPD mutations, increases skin cells’ longevity and healthy functionality. Consequentially, G+C Complex CLR™ slows down the skin aging process by interfering with the production of inflammatory mediators involved in the ‘inflammaging’ processes.

CutiGuard CLRTM

Based on the extremophile red alga Galdieria sulphuraria, CutiGuard CLR™ constitutes a refined approach to the first signs of skin aging. It transfers the adaptivity and resilience of Galdieria sulphuraria to a highly effective, natural active ingredient that protects the skin in stressful environments.

Skin aging starts in the skin cells, which, during a lifetime, accumulate damage. Extrinsic and intrinsic factors add damage, leading to prolonged inflammation and cell senescence. CutiGuard CLR™ reduces the number of senescent cells and associated inflammatory and destructive mediators which lead to visible skin aging. It thus protects skin against premature aging. CutiGuard CLR™ also reduces wrinkles and significantly improves skin smoothness as well as the evenness of skin color – three crucial factors for a healthy and young appearance.

With its proactive and preventive approach, CutiGuard CLR™ is extremely suitable for modern aging consumers. It slows down the skin aging process and helps to avoid the development of the first signs of skin aging.

CutiBiome CLRTM

CutiBiome CLR™ is a synergistic complex of lipophilic extracts from Manuka, Black Pepper and Magnolia. It provides essential support for the natural balance between skin and its microbiota in difficult situations, like acne and dandruff.

The active reduces the film forming activity and significantly inhibits the growth of virulent phylotypes of Cutibacterium acnes. It strongly reduces inflammation involved in acne and dandruff. In vitro and in vivo studies show that it strongly reduces inflammation involved in acne and dandruff. On people suffering from acne, the use of CutiBiome CLR™ leads to a dramatic and perceivable reduction of sebum production, comedones, pustules and pimples.

CutiBiome CLR™ was also shown to reduce expression of 5α-reductase and the production of inflammatory mediators. In vivo studies showed potent reduction of dandruff. CutiBiome CLR™ supports the scalp microbiota to return to its normal healthy state, more effectively than Piroctone Olamine. It also outperforms this benchmark ingredient in reducing scalp oiliness, scalp sensitivity and itch.

AnnonaSense CLRTM

AnnonaSense CLR™ provides the skin with means to establish a sustainable homeostatic balance, improving skin health and well-being. The potent adaptogenic action of AnnonaSense CLR™ supports the skin’s endocannabinoid system by activating the CB2 receptor. Through this action, it reduces inflammatory processes induced by TRPV1. Histamine-, as well as TNFα/Substance P-induced stress is down-regulated and the expression of a vital detrimental receptor in skin, IL-31RA, is decreased. AnnonaSense CLR™ makes the skin less sensitive and more balanced, even itch is perceivably reduced. Skin appearance is improved and the perception of well-being and quality of life is enhanced.

AnnonaSense CLR™ is obtained from Annona cherimola, common name Cherimoya, an edible fruit originating from South America.

CutiFine CLRTM

CutiFine CLR™ refines skin texture and complexion with soft focus. Conspicuous skin pores are a great concern for consumers, especially for those who have oily and combination skin. As skin ages, skin pores become also more pronounced, making skin pores the latest anti-aging skincare goal for consumers and skincare brands alike.

Based on a synergistic combination of extracts of Vaccaria segetalis (Cowherb) and Adansonia digitata (Baobab) pulp, CutiFine CLR™ is an all-natural, safe and effective skincare active which goes to the core of the causes leading to conspicuous pores.  It works on all important biological processes which lead to pore enlargement, but also reduces the colour contrast of the pores with the surrounding skin, an until now largely overlooked but essential feature. CutiFine CLR™ constitutes an all-in-one approach to reduce the conspicuousness of pores.

Wheat Germ Oil CLR

Wheat Germ Oil CLR is particularly suitable for skin protection concepts and the care of sensitive and severely dry skin and lips. Wheat Germ Oil has an extensive history of use. For centuries, it has been used for a wide variety of skincare applications, for instance for its healing properties and for the treatment of many different skin ailments.

Wheat Germ Oil CLR is obtained from freshly milled wheat germs renowned for their high antioxidant content.

St.John’s Wort Oil CLR

St. John’s Wort Oil CLR is particularly suitable for the care of dry, sensitive and problem skin, chapped lips, and in the support of irritated skin. St. John’s Wort has been traditionally used in medicinal applications to treat insect bites, sunburn, bruises and edema.

St. John’s Wort Oil CLR contains the lipophilic components of the aerial parts of the St. John‘s Wort plant (Hypericum perforatum), collected when in blossom and gently extracted in olive oil.

Carrot Oil CLR

Carrot Oil CLR is especially suitable for anti-aging skin care, sun and after-sun care, and all skincare concepts for obtaining an even and harmonious skin color. Carrots are renowned for their high content of ß-carotene, which is further enriched in Carrot Oil CLR to obtain optimal results for the skin, providing skin with much needed protection.
Carrot Oil CLR is a lipophilic extract of Daucus carota sativa in stabilized soybean oil, enriched with anti-oxidative ß-carotene to 3,300 IU/g.

Arnica Oil CLR

Arnica Oil CLR is suitable for a wide variety of skin and haircare concepts, such as anti–hair loss, relief for troubled skin, and after-sun care. Arnica is renowned for its ability to stimulate and heal the skin, which is illustrated by its extensive use in the treatment of bruises and sprains. It is also known for its calming and soothing properties.
Arnica Oil CLR is obtained by an extremely mild extraction of the blossoms of Arnica montana in stabilized soybean oil.

Calendula Oil CLR

Calendula Oil CLR is particularly suitable for skin and haircare concepts where soothing and calming properties are valued, such as baby care, care for sensitive skin, elderly skin and irritated scalp. Calendula has been extensively used in both traditional and modern medicine for its well-described
anti-inflammatory properties.
Calendula Oil CLR is obtained by an extremely mild extraction of the blossoms of Calendula officinalis in stabilized soybean oil.

Soluvit Richter NP

Soluvit Richter NP is suitable for a wide variety of skin and haircare concepts, such as the treatment of eye bags, dark circles, bruises and the care of tired legs and nails, but also for anti–hair loss.
Soluvit Richter NP is based on an extract of horse chestnut enriched with vitamins A, E, F, H (biotin) and vitamins of the B group. Horse chestnut has a rich history of use in traditional and modern medicine, especially for its stimulating and energizing properties. The vitamins show an extensive range of potential benefits for both skin and hair.

SedaplantTM Richter

Sedaplant™ Richter is applicable in a wide variety of skin and haircare concepts, such as baby care, and care for sensitive skin and scalp.
Sedaplant™ Richter contains potent mixtures of extracts from fennel, hops, chamomile, balm mint, mistletoe and yarrow, as well as urea and allantoin. All ingredients are well known and well appreciated in both traditional medicine and modern science, especially for their skin-healing and soothing properties.

HexaplantTM Richter

Hexaplant™ Richter is applicable in a wide variety of skin and haircare concepts, such as baby care, and care for sensitive skin and scalp.
Hexaplant™ Richter contains potent mixtures of extracts from fennel, hops, chamomile, balm mint, mistletoe and yarrow. All ingredients are well known and well appreciated in both traditional medicine and modern science, especially for their skin-healing and soothing properties.

Maricol S

Due to its film-forming and skin-protective properties, Maricol S is especially suitable for the care of dry and mature skin as well as skin stressed by negative environmental influences.
Maricol S is a native soluble collagen of marine origin, obtained from fish skin.

Ceramide Complex CLR TM PE-F

Ceramide Complex CLR™ PE-F supplies skin with structural elements and supports the recovery and maintenance of the skin’s healthy barrier function and water-holding capacity.

Ceramide Complex CLR™ PE-F contains phyto lipids in lamellar, liquid crystalline form. The plant-derived lipid mixture consists of phospholipids and sphingolipids. It is easily able to penetrate skin and also moisturizes hair.

GlycodermTM (P)

Glycoderm™ (P) is a liposomal moisturizer, where plant derived liposomal bilayers contain biotechnologically produced hyaluronic acid and natural blossom honey. Its liposomal structure supports quick absorption of hyaluronic acid and blossom honey.

Consequently, Glycoderm™ (P) constitutes a polyvalent approach toward skin hydration by supporting the maintenance and recovery of the skin’s lipid barrier function and supplying the skin with essential ingredients that are able to bind water and moisturize skin.

HygroplexTM HHG

Hygroplex™ HHG is a physiological moisturizer, specifically designed to be fully adapted to the water-binding capacity of human skin, containing ingredients similar to the Natural Moisturizing Factors (NMF) in the skin. It is extremely suitable for skincare concepts for dry and aged skin and can be used in any skincare application for any type of skin which needs hydration. It effectively moisturizes and smoothes the skin.

Additionally, it has shown to be a potent moisturizer for hair, increasing its water content and improving its mechanical properties.

Also available as Hygroplex™ WHN without hexyl nicotinate.

ProBarrierTM CLR

ProBarrier™ CLR, a suspension of waxy particles based on caprylic/capric triglycerides and Copernicia cerifera (carnauba) wax, is a highly technological skincare ingredient which creates a persistent but non-occlusive film on the skin.

It is especially designed for cosmetic formulations which aim to shield the skin against harsh environmental conditions, providing an extra layer of protection and an excellent light skin feel.

DayMoist CLRTM

DayMoist CLR™ potently and immediately increases the concentration of the natural moisturizing factors (NMF) in the upper layers of the skin, resulting in immediate and long-lasting moisturizing effects. These results were obtained by making use of Confocal Raman Microspectroscopy and analyzing skin capacitance.

DayMoist CLR™ also is a hair conditioner, improving hair combability and manageability. Additionally, it was shown to positively influence the mechanical properties of hair and to protect against fading of hair color in dyed hair. DayMoist CLR™ also effectively protects hair against heat that is applied during hair straightening.

DayMoist CLR™ is a complex of natural plant-derived active ingredients.

Vitamin F Forte

Vitamin F forte nurtures, protects and acts as a skin conditioner. It is particularly suitable for the treatment of dry, stressed and sensitive skin, potently supporting the skin in rebuilding and maintaining its natural healthy structure and functionality.

Vitamin F forte also is a strong hair conditioner, improving hair combability, and has shown to protect against hair breakage.

Vitamin F forte contains natural polyunsaturated essential free fatty acids originating from safflower oil, with a particularly high content of linoleic acid.

Also available as Vitamin F water-soluble CLR in watersoluble form. 

ModukineTM

Modukine™ is a milk-derived active ingredient which is specifically designed for the effective regenerative care of sensitive, dry and troubled skin. It is intended for any type of skin which shows chronic and pronounced inflammation.

Modukine™ acts as an extremely potent biological cell response modifier. It strongly reduces inflammatory processes in the skin at a cellular level and helps to restore skin barrier and normal skin functionality.

ProBioBalance CLRTM NP

ProBioBalance CLR™ NP activates cellular processes involved in cellular nutrition and helps activate detoxification processes. The metabolic activity of skin cells is increased, and the skin’s immune system strengthened and protected against environmental stress. The application of ProBioBalance CLR™ NP leads to reduction of skin inflammation and also actively prepares skin for external stresses.

ProBioBalance CLR™ NP consists of postbiotic bifido cultures which are suspended and disintegrated in a biologically active milk-based matrix.

PhytoDefense CLRTM

PhytoDefense CLR™ is especially designed for the care of hyper-reactive and irritable skin. It essentially reduces the sensitivity of skin by its goal-oriented approach to the most important features of sensitive skin: burning/stinging/itching sensations and skin redness. Skin irritations as well as skin redness are noticeably reduced.
PhytoDefense CLR™ is obtained from Magnolia grandiflora, known in traditional medicine for its potent calming and soothing properties.

Repair Complex CLRTM PF

Repair Complex CLR™ PF is a biotechnological anti-aging active, obtained from a lysate of probiotic bifidobacteria, which potently protects against UV-induced damage in the skin. UV radiation leads to skin cell damage and immunosuppression, a deactivation of the local immune system in the skin.
By effectively activating anti-immunosuppressive processes on the cellular level, Repair Complex CLR™ PF increases cellular repair and potently supports the skin’s endogenous protection mechanisms. Repair Complex CLR™ PF thus counteracts premature skin aging, i.e. photoaging.

LactokineTM Fluid PF

Lactokine™ Fluid PF is a multifunctional agent, suitable for a wide variety of skincare concepts. It effectively soothes and calms skin, accelerating the reduction of skin redness and irritation after external stresses. Additionally, Lactokine™ Fluid PF vitalizes and energizes skin cells and induces the synthesis of collagen, yielding skin smoothing and firming properties, thus making it a potent anti-aging product. In other in vivo studies Lactokine™ Fluid PF was shown to be very effective in skin lightening, reducing the production of melanin.
Lactokine™ Fluid PF contains a network of activated and stabilized signal molecules derived from milk.

FollicusanTM DP

Follicusan™ DP stimulates the functionality of the dermal papilla cells at the base of the hair follicles, thus counteracting premature hair loss. It increases the number of anagen hair follicles (growth stage) and decreases that of telogen hair follicles (resting stage). Hair density as well as cumulative hair thickness is increased.
Follicusan™ DP contains biologically active signaling proteins, ethyl panthenol (provitamin B5), inositol as well as acetyl cysteine and acetyl methionine in a water-ethanol medium.

PhytosanTM K

Phytosan™ K exerts a potent influence against skin aging. It activates cellular repair processes, supporting the maintenance of cellular integrity and energy after UV irradiation. Both are important factors in counteracting photoaging.
Phytosan™ K also has potent regenerative effects, such as stimulation of collagen synthesis. This results in improved skin firmness and smoothness and a reduction of wrinkle depth. Phytosan™ K counteracts biological and UV-induced premature aging of the skin.
Phytosan™ K contains proteins, glycoproteins, and polysaccharides isolated from organic soybeans (GMO-free).

SyriCalmTM CLR (PC)

SyriCalm™ is a natural product derived from Poria cocos and Phragmites. It effectively reduces inflammation and strongly supports skin in dealing with external stresses.
Additionally, SyriCalm™ is designed to give effective support where the skin is challenged by environmental stress, e.g. shaving, depilation or daily hygiene. It helps the skin recover its natural balance.
Available as SyriCalm™ CLR (PC) and SyriCalm™ CLR.

MPCTM -Milk Peptide Complex

MPC™ reduces the visible signs of aging by reactivating skin cells and inducing the production of extracellular matrix molecules in the dermis, such as collagen Type I, hyaluronic acid and fibronectin. In vivo studies have shown that formulations with MPC™ make the skin firmer and improve its elasticity. MPC™ quickly and effectively reduces wrinkle depth and improves the structure of the skin.
MPC™– Milk Peptide Complex contains a complex of activated natural signaling molecules derived from milk, such as TGF-β.

BelidesTM ORG

Belides™ ORG is a natural skin-lightening agent, derived from organic daisy flowers (Bellis perennis). It is suitable for any skincare concept providing even and luminous complexion and radiant skin.
Belides™ ORG’s action is based on a potent, multifaceted reduction in the activity of melanocytes. Belides™ ORG influences different cellular pathways involved in melanogenesis, encompassing the reduction of cellular signaling, tyrosinase transcription, tyrosinase activity and melanosome transfer. These actions lead to even pigmentation and make age spots less visible.
Also available as Belides™ NP.

ProRenew Complex CLRTM

ProRenew Complex CLR™ acts on essential features in the aging process of the skin, its ability to successfully adapt to a constantly changing environment and to effectively renew itself.

ProRenew Complex CLR™ positively influences the speed and quality of epidermal growth. It has shown to effectively promote desquamation, the shedding of dead cells. ProRenew Complex CLR™ is beneficial for both the health of skin and the skin microbiota. It balances and protects the skin microbiota and supports it in dealing with day-to-day stress.

ProRenew Complex CLR™ also improves the condition of the scalp and makes it less oily. It additionally leads to perceivable reduction of the sensitivity of the scalp, makes scalp tangibly healthier and reduces attributes related to dryness of the scalp. ProRenew Complex CLR™ provides important support for the skin and the scalp, even from rinse-off formulations.

JuvenEye CLRTM

Based on a synergistic combination of extracts of Hieracium pilosella and the flowers of Bellis perennis, JuvenEye CLR™ addresses the most important dermatological processes in the formation and persistence of dark circles. It activates vital processes which allow for the breakdown of heme, which is both dark-colored and plays an important role in the etiology of dark circles. JuvenEye CLR™ also activates dermal draining, through its ability to increase the production of VEGF-C. Excess fluids, electrolytes and immune cells are drained away more effectively. With JuvenEye CLR™ melanin deposition in the skin is reduced and overall skin health is improved.

In in vivo studies where JuvenEye CLR™ was compared with a corresponding placebo-formulation it could be seen that JuvenEye CLR™ clearly reduces the visibility of dark circles. Both the color and the surface area of dark circles were reduced significantly.

MultiMoist CLRTM

MultiMoist CLR™ activates production of the vitamin D receptor (VDR) and promotes the VDR’s activation. MultiMoist CLR™ also potentiates the effect of vitamin D. As a consequence the skin becomes more moisturized. By making use of 5 different objective instrumental approaches, the immediate and long term moisturizing properties of MultiMoist CLR™ were convincingly proven. Additionally, the activity of MultiMoist CLR™ was proven in a consumer study, where the subjective improvement of skin moisture content, skin smoothness and the look of skin were confirmed.

In addition, MultiMoist CLR™ binds water in the cortex of hair, improving a variety of important hair qualities. It is a hair conditioner, improving its combability and handling. MultiMoist CLR™ also protects against color fading caused by repeated washing with shampoo. It dramatically reduces hair breakage from combing and MultiMoist CLR™ has a strong impact on static flyaway too. Hair frizziness is significantly reduced as well.

MultiMoist CLR™ consists of a powerful synergistic blend of fructooligosaccharides and beta vulgaris (beet) root extract.

G+C Complex CLRTM

G+C Complex CLR™ is based on almost 50 years of scientific research on the effect of Bifida Ferment Lysate on skin aging. With its natural next generation approach, it acts on the core of skin aging, the ability to compensate for the threefold negative effects of sunlight on the biogenetic code of skin: DNA damage, immunosuppression and dysregulation of the circadian rhythm. G+C Complex CLR™  provides essential support to the skin cells. It acts on UV-induced immunosuppression and brings balance to the circadian rhythm of skin cells, allowing for effective DNA repair.

G+C Complex CLR™ induces the repair of persistent CPD mutations, increases skin cells’ longevity and healthy functionality. Consequentially, G+C Complex CLR™ slows down the skin aging process by interfering with the production of inflammatory mediators involved in the ‘inflammaging’ processes.

CutiGuard CLRTM

Based on the extremophile red alga Galdieria sulphuraria, CutiGuard CLR™ constitutes a refined approach to the first signs of skin aging. It transfers the adaptivity and resilience of Galdieria sulphuraria to a highly effective, natural active ingredient that protects the skin in stressful environments.

Skin aging starts in the skin cells, which, during a lifetime, accumulate damage. Extrinsic and intrinsic factors add damage, leading to prolonged inflammation and cell senescence. CutiGuard CLR™ reduces the number of senescent cells and associated inflammatory and destructive mediators which lead to visible skin aging. It thus protects skin against premature aging. CutiGuard CLR™ also reduces wrinkles and significantly improves skin smoothness as well as the evenness of skin color – three crucial factors for a healthy and young appearance.

With its proactive and preventive approach, CutiGuard CLR™ is extremely suitable for modern aging consumers. It slows down the skin aging process and helps to avoid the development of the first signs of skin aging.

CutiBiome CLRTM

CutiBiome CLR™ is a synergistic complex of lipophilic extracts from Manuka, Black Pepper and Magnolia. It provides essential support for the natural balance between skin and its microbiota in difficult situations, like acne and dandruff.

The active reduces the film forming activity and significantly inhibits the growth of virulent phylotypes of Cutibacterium acnes. It strongly reduces inflammation involved in acne and dandruff. In vitro and in vivo studies show that it strongly reduces inflammation involved in acne and dandruff. On people suffering from acne, the use of CutiBiome CLR™ leads to a dramatic and perceivable reduction of sebum production, comedones, pustules and pimples.

CutiBiome CLR™ was also shown to reduce expression of 5α-reductase and the production of inflammatory mediators. In vivo studies showed potent reduction of dandruff. CutiBiome CLR™ supports the scalp microbiota to return to its normal healthy state, more effectively than Piroctone Olamine. It also outperforms this benchmark ingredient in reducing scalp oiliness, scalp sensitivity and itch.

AnnonaSense CLRTM

AnnonaSense CLR™ provides the skin with means to establish a sustainable homeostatic balance, improving skin health and well-being. The potent adaptogenic action of AnnonaSense CLR™ supports the skin’s endocannabinoid system by activating the CB2 receptor. Through this action, it reduces inflammatory processes induced by TRPV1. Histamine-, as well as TNFα/Substance P-induced stress is down-regulated and the expression of a vital detrimental receptor in skin, IL-31RA, is decreased. AnnonaSense CLR™ makes the skin less sensitive and more balanced, even itch is perceivably reduced. Skin appearance is improved and the perception of well-being and quality of life is enhanced.

AnnonaSense CLR™ is obtained from Annona cherimola, common name Cherimoya, an edible fruit originating from South America.

CutiFine CLRTM

CutiFine CLR™ refines skin texture and complexion with soft focus. Conspicuous skin pores are a great concern for consumers, especially for those who have oily and combination skin. As skin ages, skin pores become also more pronounced, making skin pores the latest anti-aging skincare goal for consumers and skincare brands alike.

Based on a synergistic combination of extracts of Vaccaria segetalis (Cowherb) and Adansonia digitata (Baobab) pulp, CutiFine CLR™ is an all-natural, safe and effective skincare active which goes to the core of the causes leading to conspicuous pores.  It works on all important biological processes which lead to pore enlargement, but also reduces the colour contrast of the pores with the surrounding skin, an until now largely overlooked but essential feature. CutiFine CLR™ constitutes an all-in-one approach to reduce the conspicuousness of pores.

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